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Evaluation of the efficacy and safety of a CS20® protective barrier gel containing OGT compared with topical aciclovir and placebo on functional and objective symptoms of labial herpes recurrences: a randomized clinical trial

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Evaluation of the efficacy and safety of a CS20® protective barrier gel containing OGT compared with topical aciclovir and placebo on functional and objective symptoms of labial herpes recurrences: a randomized clinical trial

Auteurs : A. Khemis [France] ; L. Duteil [France] ; A. C. Coudert [France] ; Y. Tillet [France] ; O. Dereure [France] ; J. P. Ortonne [France]

Source :

Journal of the European Academy of Dermatology and Venereology [ 0926-9959 ] ; 2012-10.

RBID : ISTEX:1450E6DD7D7326D61875E2B7F534873A886626BC

English descriptors

Abstract

Background Topical or systemic antiviral drugs reduce the duration of herpes simplex virus 1 (HSV‐1) recurrences but may not alleviate functional symptoms.

Url:

https://api.istex.fr/document/1450E6DD7D7326D61875E2B7F534873A886626BC/fulltext/pdf

DOI: 10.1111/j.1468-3083.2011.04269.x

Affiliations:

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<author><name sortKey="Dereure, O" sort="Dereure, O" uniqKey="Dereure O" first="O." last="Dereure">O. Dereure</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aciclovir</term>
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<term>Acyclovir cream</term>
<term>Antimicrob agents chemother</term>
<term>Antiviral</term>
<term>Antiviral activity</term>
<term>Authors journal</term>
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<term>Herpes episode</term>
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<term>Intensity score</term>
<term>Jeadv</term>
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<term>Labial herpes</term>
<term>Labial recurrences</term>
<term>Labialis</term>
<term>Lesion</term>
<term>Lesion repair</term>
<term>Oedema</term>
<term>Oral lubricant solution</term>
<term>Oxygenated glycerol triesters</term>
<term>Pain intensity score</term>
<term>Penciclovir</term>
<term>Penciclovir cream</term>
<term>Percentage reduction</term>
<term>Placebo</term>
<term>Placebo group</term>
<term>Protective barrier</term>
<term>Randomized</term>
<term>Recurrence</term>
<term>Recurrent herpes labialis</term>
<term>Recurrent labial herpes</term>
<term>Secondary endpoints</term>
<term>Simplex</term>
<term>Subjective scores</term>
<term>Time point</term>
<term>Topical</term>
<term>Topical aciclovir</term>
<term>Topical aciclovir group</term>
<term>Topical therapy</term>
<term>Treatment groups</term>
<term>Unsightly appearance</term>
<term>Venereology</term>
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<term>Antimicrob agents chemother</term>
<term>Antiviral</term>
<term>Antiviral activity</term>
<term>Authors journal</term>
<term>Baseline</term>
<term>Clinical scores</term>
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<term>Endpoint</term>
<term>European academy</term>
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<term>Herpes simplex labialis</term>
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<term>Labial</term>
<term>Labial herpes</term>
<term>Labial recurrences</term>
<term>Labialis</term>
<term>Lesion</term>
<term>Lesion repair</term>
<term>Oedema</term>
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<term>Oxygenated glycerol triesters</term>
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<front><div type="abstract">Background  Topical or systemic antiviral drugs reduce the duration of herpes simplex virus 1 (HSV‐1) recurrences but may not alleviate functional symptoms.</div>
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Evaluation of the efficacy and safety of a CS20® protective barrier gel containing OGT compared with topical aciclovir and placebo on functional and objective symptoms of labial herpes recurrences: a randomized clinical trial

Evaluation of the efficacy and safety of a CS20® protective barrier gel containing OGT compared with topical aciclovir and placebo on functional and objective symptoms of labial herpes recurrences: a randomized clinical trial

Source :

English descriptors

Abstract

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